FliD

• Description: flagellar hook-associated protein 2 (HAP2)
  
  

Gene name	fliD
Synonyms
Essential	no
Product	flagellar hook-associated protein 2 (HAP2)
Function	motility and chemotaxis
Interactions involving this protein in SubtInteract: FliD
MW, pI	54 kDa, 4.804
Gene length, protein length	1494 bp, 498 aa
Immediate neighbours	fliS, yvyC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

• Locus tag: BSU35340

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: fliD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • FlhA-FliD PubMed
  • FliD-FliT PubMed
  • FlhA-(FliD-FliT) PubMed

• Localization: secreted (according to Swiss-Prot), extracellular (no signal peptide) PubMed

Database entries

• Structure:

• UniProt: P39738

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yvyC-fliD-fliS-fliT PubMed

• Sigma factor: SigD PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Gert Bange, Nico Kümmerer, Christoph Engel, Gunes Bozkurt, Klemens Wild, Irmgard Sinning
FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system.
Proc Natl Acad Sci U S A: 2010, 107(25);11295-300
[PubMed:20534509] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

L Chen, J D Helmann
The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.
J Bacteriol: 1994, 176(11);3093-101
[PubMed:8195064] [WorldCat.org] [DOI] (P p)