DivIB

• Description: cell-division initiation protein (septum formation)
  
  

Gene name	divIB
Synonyms	dds, tms-12
Essential	yes PubMed
Product	cell-division protein
Function	septum formation
Metabolic function and regulation of this protein in SubtiPathways: Cell wall
MW, pI	30 kDa, 9.244
Gene length, protein length	789 bp, 263 aa
Immediate neighbours	murB, ylxW
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell division, sporulation proteins, cell envelope stress proteins (controlled by SigM, W, X, Y), essential genes, membrane proteins

This gene is a member of the following regulons

SigE regulon, SigM regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU15240

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ftsQ family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PbpB-DivIB-(FtsL-DivIC)2 PubMed, as part of the divisome
  • WalK-DivIB PubMed

• Localization: cell membrane PubMed

Database entries

• Structure: 2ALJ (major extracytoplasmic domain, Geobacillus stearothermophilus)

• UniProt: P16655

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• • murE-mraY-murD-spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • divIB-ylxW-ylxX-sbp PubMed

• Sigma factor:
  • spoVE: SigE PubMed
  • murG: SigMPubMed
  • divIB: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: