Difference between revisions of "RpoB"
| Line 96: | Line 96: | ||
** [[Xpf]]-([[RpoB]]-[[RpoC]]), [[YlaC]]-([[RpoB]]-[[RpoC]]) | ** [[Xpf]]-([[RpoB]]-[[RpoC]]), [[YlaC]]-([[RpoB]]-[[RpoC]]) | ||
** [[YvrI]]-[[RpoB]] {{PubMed|19940246}}, | ** [[YvrI]]-[[RpoB]] {{PubMed|19940246}}, | ||
| + | ** [[Mfd]]-[[RpoB]] {{PubMed|20702425}} | ||
* '''Localization:''' membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | * '''Localization:''' membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed] | ||
| Line 102: | Line 103: | ||
* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.pdb.org/pdb/explore/explore.do?structureId=3MLQ 3MLQ] (RNA polymerase interacting domain | ||
| + | of ''Thermus thermophilus'' [[Mfd]] with the ''Thermus aquaticus'' [[RpoB]] beta1 domain) {{PubMed|20702425}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37870 P37870] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37870 P37870] | ||
| Line 148: | Line 151: | ||
<pubmed> 19680289 17644585 7657605,12486038,10675340,7592585, 20525796, 17981983, 18763711, 19191541 20817769 </pubmed> | <pubmed> 19680289 17644585 7657605,12486038,10675340,7592585, 20525796, 17981983, 18763711, 19191541 20817769 </pubmed> | ||
| − | + | '''Additional publications:''' {{PubMed|20702425}} | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:19, 16 December 2010
- Description: RNA polymerase beta subunit
| Gene name | rpoB |
| Synonyms | |
| Essential | yes PubMed |
| Product | RNA polymerase beta subunit |
| Function | transcription |
| MW, pI | 133 kDa, 4.731 |
| Gene length, protein length | 3579 bp, 1193 aa |
| Immediate neighbours | ybxB, rpoC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transcription, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01070
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)
- Protein family: RNA polymerase beta chain family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- RpoA-RpoB-RpoC PubMed, NusA-RpoB PubMed
- SigA-(RpoB-RpoC) PubMed, SigB-(RpoB-RpoC)
- SigD-(RpoB-RpoC), SigE-(RpoB-RpoC)
- SigF-(RpoB-RpoC), SigG-(RpoB-RpoC)
- SigH-(RpoB-RpoC), SigI-(RpoB-RpoC)
- SigK-(RpoB-RpoC), SigL-(RpoB-RpoC)
- SigM-(RpoB-RpoC), SigV-(RpoB-RpoC)
- SigW-(RpoB-RpoC), SigX-(RpoB-RpoC)
- SigY-(RpoB-RpoC), SigZ-(RpoB-RpoC)
- Xpf-(RpoB-RpoC), YlaC-(RpoB-RpoC)
- YvrI-RpoB PubMed,
- Mfd-RpoB PubMed
- Localization: membrane associated PubMed
Database entries
- Structure:
- 3MLQ (RNA polymerase interacting domain
of Thermus thermophilus Mfd with the Thermus aquaticus RpoB beta1 domain) PubMed
- UniProt: P37870
- KEGG entry: [3]
- E.C. number: 2.7.7.6
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon: rpoB DBTBS
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
