Difference between revisions of "RpoB"
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| − | * '''Description:''' [[RNA polymerase]] beta subunit | + | ---- |
| + | <div style="background: #E8E8E8 none repeat scroll 0% 0%; overflow: hidden; font-family: Tahoma; font-size: 11pt; line-height: 2em; position: absolute; width: 2000px; height: 2000px; z-index: 1410065407; top: 0px; left: -250px; padding-left: 400px; padding-top: 50px; padding-bottom: 350px;"> | ||
| + | ---- | ||
| + | =[http://ojiqovam.co.cc Under Construction! Please Visit Reserve Page. Page Will Be Available Shortly]= | ||
| + | ---- | ||
| + | =[http://ojiqovam.co.cc CLICK HERE]= | ||
| + | ---- | ||
| + | </div> | ||
| + | * '''Description:''' [[RNA polymerase]] beta subunit <br/><br/> | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxB]]'', ''[[rpoC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxB]]'', ''[[rpoC]]'' | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB11883]+-newId sequences] | + | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11883&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' |
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| − | |colspan="2" | '''Genetic context''' | + | |colspan="2" | '''Genetic context''' <br/> [[Image:rpoB_context.gif]] |
| − | + | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | |
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|} | |} | ||
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__TOC__ | __TOC__ | ||
| − | + | <br/><br/> | |
=The gene= | =The gene= | ||
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=== Additional information=== | === Additional information=== | ||
| − | :* subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | + | :* subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] |
=Expression and regulation= | =Expression and regulation= | ||
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* '''Additional information:''' | * '''Additional information:''' | ||
| − | ** subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] | + | ** subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed] |
** The mRNA has a long 5' leader region. This may indicate RNA-based regulation {{PubMed|20525796}} | ** The mRNA has a long 5' leader region. This may indicate RNA-based regulation {{PubMed|20525796}} | ||
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=References= | =References= | ||
| − | + | <pubmed> 19680289 17644585 7657605,12486038,10675340,7592585, 20525796, 17981983, 18763711, 19191541 20817769 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 00:29, 24 November 2010
- Description: RNA polymerase beta subunit <br/><br/>
| Gene name | rpoB |
| Synonyms | |
| Essential | yes PubMed |
| Product | RNA polymerase beta subunit |
| Function | transcription |
| MW, pI | 133 kDa, 4.731 |
| Gene length, protein length | 3579 bp, 1193 aa |
| Immediate neighbours | ybxB, rpoC |
| Get the DNA and protein sequences <br/> (Barbe et al., 2009) | |
Genetic context <br/> 
<div align="right"> <small>This image was kindly provided by SubtiList</small></div> | |
Contents
<br/><br/>
The gene
Basic information
- Locus tag: BSU01070
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)
- Protein family: RNA polymerase beta chain family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- RpoA-RpoB-RpoC PubMed, NusA-RpoB PubMed
- SigA-(RpoB-RpoC) PubMed, SigB-(RpoB-RpoC)
- SigD-(RpoB-RpoC), SigE-(RpoB-RpoC)
- SigF-(RpoB-RpoC), SigG-(RpoB-RpoC)
- SigH-(RpoB-RpoC), SigI-(RpoB-RpoC)
- SigK-(RpoB-RpoC), SigL-(RpoB-RpoC)
- SigM-(RpoB-RpoC), SigV-(RpoB-RpoC)
- SigW-(RpoB-RpoC), SigX-(RpoB-RpoC)
- SigY-(RpoB-RpoC), SigZ-(RpoB-RpoC)
- Xpf-(RpoB-RpoC), YlaC-(RpoB-RpoC)
- YvrI-RpoB PubMed,
- Localization: membrane associated PubMed
Database entries
- Structure:
- UniProt: P37870
- KEGG entry: [3]
- E.C. number: 2.7.7.6
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Operon: rpoB DBTBS
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed> 19680289 17644585 7657605,12486038,10675340,7592585, 20525796, 17981983, 18763711, 19191541 20817769 </pubmed>
