Difference between revisions of "DhbA"
| Line 99: | Line 99: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[Fur]]: transcription repression {{PubMed|12354229}} | ** [[Fur]]: transcription repression {{PubMed|12354229}} | ||
| + | ** [[AbrB]]: transcription repression {{PubMed|20817675}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 123: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>8224884,10400588,11112781 ,11790741,12354229, 8921902 8550523 20525796</pubmed> | + | <pubmed>8224884,10400588,11112781 ,11790741,12354229, 8921902 8550523 20525796 20817675</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:15, 15 September 2010
- Description: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
| Gene name | dhbA |
| Synonyms | entA |
| Essential | no |
| Product | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase |
| Function | biosynthesis of the siderophore bacillibactin |
| MW, pI | 27 kDa, 5.311 |
| Gene length, protein length | 783 bp, 261 aa |
| Immediate neighbours | dhbC, besA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU32000
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH (according to Swiss-Prot)
- Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39071
- KEGG entry: [3]
- E.C. number: 1.3.1.28
Additional information
Expression and regulation
- Additional information:
- The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
