Difference between revisions of "Sr1"
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| − | * '''Description:''' small regulatory RNA controlling [[AhrC]] expression<br/><br/> | + | * '''Description:''' small regulatory RNA controlling [[AhrC]] expression, peptide controlling the stability of the ''[[cggR]]-[[gapA]]'' mRNA <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || small regulatory RNA/ regulatory peptide | |style="background:#ABCDEF;" align="center"| '''Product''' || small regulatory RNA/ regulatory peptide | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of arginine metabolism | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of arginine metabolism and glycolysis |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4.4 kDa, 3.89 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4.4 kDa, 3.89 | ||
| Line 74: | Line 74: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' the peptide controls the stability of the ''[[cggR]]-[[gapA]]'' mRNA {{PubMed|20444087}} |
* '''Protein family:''' the peptide is conserved in bacilli | * '''Protein family:''' the peptide is conserved in bacilli | ||
| Line 92: | Line 92: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' ** [[GapA]]-[[YkzW]] {{PubMed|20444087}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 136: | Line 136: | ||
=References= | =References= | ||
| − | <pubmed>16164558 17020585 17576690, </pubmed> | + | <pubmed>16164558 17020585 17576690, 20444087 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:43, 11 May 2010
- Description: small regulatory RNA controlling AhrC expression, peptide controlling the stability of the cggR-gapA mRNA
| Gene name | sr1 |
| Synonyms | ykzW |
| Essential | no |
| Product | small regulatory RNA/ regulatory peptide |
| Function | control of arginine metabolism and glycolysis |
| MW, pI | 4.4 kDa, 3.89 |
| Gene length, protein length | 205 bp (RNA), 120 bp (ORF), 39 aa |
| Immediate neighbours | slp, speA |
| Gene sequence | |
Genetic context 
| |
Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
Additional information
Located between the slp and speA genes.
The RNA
Basic information/ Evolution
- Catalyzed reaction/ biological activity: hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed
Extended information on the RNA
- Kinetic information
- Localization
Database entries
- Structure:
Additional information
Information on the structure of the RNA can be found in Heidrich et al., 2006
The peptide
Basic information/ Evolution
- Catalyzed reaction/ biological activity: the peptide controls the stability of the cggR-gapA mRNA PubMed
- Protein family: the peptide is conserved in bacilli
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: C0H410
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Operon: sr1 PubMed
- Regulatory mechanism: transcription repression PubMed
- Additional information:
Biological materials
- Mutant: 168 sr1::cat, available in Brantl lab
- Expression vector:
- lacZ fusion:
Labs working on this gene/protein
Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage
Your additional remarks
References
