Difference between revisions of "FabHA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid biosynthesis | ||
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+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_syn.html Lipid synthesis]''' | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.045 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.045 |
Revision as of 13:37, 16 February 2010
- Description: beta-ketoacyl-acyl carrier protein synthase III
Gene name | fabHA |
Synonyms | yjaX , fabH1 |
Essential | no |
Product | beta-ketoacyl-acyl carrier protein synthase III |
Function | fatty acid biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
MW, pI | 33 kDa, 5.045 |
Gene length, protein length | 936 bp, 312 aa |
Immediate neighbours | yjzB, fabF |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU11330
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacyl-[acyl-carrier-protein] + CoA + CO2 (according to Swiss-Prot)
- Protein family: fabH family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: O34746
- KEGG entry: [3]
Additional information
- affinity for butyryl-CoA, but prefers acetyl-CoA in fatty acid biosynthesis PubMed
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications