Difference between revisions of "FtsH"
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− | <pubmed>10913836,12533473,9076729,10851010,9084181,15386101,10077851,19332814,12884008,7608085,9352926,, 19332814, 18763711 </pubmed> | + | <pubmed>10913836,12533473,9076729,10851010,9084181,15386101,10077851,19332814,12884008,7608085,9352926,, 19332814, 18763711 12176385 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 14:26, 3 February 2010
- Description: ATP-dependent metalloprotease
Gene name | ftsH |
Synonyms | |
Essential | no |
Product | ATP-dependent metalloprotease |
Function | cell division, sporulation initiation |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 70 kDa, 5.841 |
Gene length, protein length | 1911 bp, 637 aa |
Immediate neighbours | hprT, coaX |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU00690
Phenotypes of a mutant
strongly reduced sporulation frequency
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: degrades Spo0E, resulting in reduced sporulation frequency in a ftsH mutant
- Protein family:
- Paralogous protein(s): YjoB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), membrane PubMed
Database entries
- UniProt: P37476
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by heat shock (class III)
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References