Difference between revisions of "EpsA"
(→Expression and regulation) |
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]'' {{PubMed|15661000}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15661000}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigA]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by [[SinR]] | + | ** repressed by [[SinR]] {{PubMed|15661000}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[SinR]]: transcription repression [ | + | ** [[SinR]]: transcription repression {{PubMed|15661000}} |
| + | ** [[SlrR]]: transcription activation {{PubMed|18647168}} | ||
| − | * '''Additional information:''' induction by sequestration of [[SinR]] by [[SinI]] [ | + | * '''Additional information:''' |
| + | ** induction by sequestration of [[SinR]] by [[SinI]] {{PubMed|15661000}} | ||
| + | ** activation by [[SlrR]] requires prior formation of the [[SlrR]]-[[SlrA]] complex {{PubMed|18647168}} | ||
=Biological materials = | =Biological materials = | ||
Revision as of 09:25, 30 December 2009
- Description: extracellular polysaccharide synthesis, putative transmembrane modulator of EpsB activity, might activate EpsB autophosphorylation and substrate phosphorylation
| Gene name | epsA |
| Synonyms | yveK |
| Essential | no |
| Product | unknown |
| Function | extracellular polysaccharide synthesis |
| MW, pI | 25 kDa, 6.071 |
| Gene length, protein length | 702 bp, 234 aa |
| Immediate neighbours | epsB, slrR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU34370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: cpsC/capA family (according to Swiss-Prot)
- Paralogous protein(s): TkmA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P71050
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Your additional remarks
References
