Difference between revisions of "HemA"
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=Expression and regulation= | =Expression and regulation= | ||
+ | * '''Operon:''' ''[[hemA]]-[[hemX]]-[[hemC]]-[[hemD]]-[[hemB]]-[[hemL]]'' {{PubMed|1672867}} | ||
− | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1672867}} | |
− | |||
− | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
− | ** | + | ** induced by hydrogen peroxide ([[PerR]]) {{PubMed|11532148}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | ** [[PerR]]: transcription repression | + | ** [[PerR]]: transcription repression {{PubMed|11532148}} |
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 20:00, 13 December 2009
- Description: glutamyl-tRNA reductase
Gene name | hemA |
Synonyms | |
Essential | no |
Product | glutamyl-tRNA reductase |
Function | porphyrin biosynthesis |
MW, pI | 50 kDa, 5.313 |
Gene length, protein length | 1365 bp, 455 aa |
Immediate neighbours | hemX, ysxD |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU28170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH (according to Swiss-Prot)
- Protein family: glutamyl-tRNA reductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P16618
- KEGG entry: [3]
- E.C. number: 1.2.1.70
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References