Difference between revisions of "ValS"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[valS]]-[[folC]]'' {{PubMed|9098041}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9098041}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** induced by valine limitation ([[T-box]]) {{PubMed|19258532}} | + | ** induced by valine limitation ([[T-box]]) {{PubMed|9098041,19258532}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[T-box]]: [[ | + | ** [[T-box]]: [[riboswitch]], transcription termination/antitermination {{PubMed|9098041,19258532}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 126: | Line 126: | ||
=References= | =References= | ||
| − | <pubmed>19258532,, </pubmed> | + | <pubmed>19258532,9098041, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:47, 13 December 2009
- Description: valyl-tRNA synthetase
| Gene name | valS |
| Synonyms | |
| Essential | yes PubMed |
| Product | valyl-tRNA synthetase |
| Function | translation |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging, Folate | |
| MW, pI | 101 kDa, 4.868 |
| Gene length, protein length | 2640 bp, 880 aa |
| Immediate neighbours | folC, ysxE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28090
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
- Protein family: ValS type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: Q05873
- KEGG entry: [3]
- E.C. number: 6.1.1.9
Additional information
Expression and regulation
- Regulatory mechanism:
- T-box: riboswitch, transcription termination/antitermination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
