Difference between revisions of "KinC"
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* '''Domains:''' two transmembrane segments, C-terminal histidine phosphotransferase domain | * '''Domains:''' two transmembrane segments, C-terminal histidine phosphotransferase domain | ||
| − | * '''Modification:''' | + | * '''Modification:''' autophosphorylation on a His residue |
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''Effectors of protein activity:''' activity is triggered by potassium leakage {{PubMed|19114652}} | * '''Effectors of protein activity:''' activity is triggered by potassium leakage {{PubMed|19114652}} | ||
| − | * '''Interactions:''' [[KinC]]-[[Spo0A]] {{PubMed|19114652}} | + | * '''Interactions:''' [[KinC]]-[[Spo0A]] {{PubMed|19114652}}, [[KinC]]-[[Spo0F]] |
| − | * '''Localization:''' cell membrane | + | * '''Localization:''' cell membrane (Heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] |
=== Database entries === | === Database entries === | ||
Revision as of 19:52, 30 November 2009
- Description: two-component sensor kinase, phosphorylates Spo0F and Spo0A, part of the phosphorelay
| Gene name | kinC |
| Synonyms | ssb |
| Essential | no |
| Product | two-component sensor kinase |
| Function | initiation of sporulation |
| MW, pI | 48 kDa, 6.225 |
| Gene length, protein length | 1284 bp, 428 aa |
| Immediate neighbours | abh, ykqA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU14490
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of Spo0F as part of the phosphorelay, but also direct phosphorylation of Spo0A PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity: activity is triggered by potassium leakage PubMed
- Localization: cell membrane (Heterogeneous) PubMed
Database entries
- Structure:
- UniProt: P39764
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: kinC (according to DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
