Difference between revisions of "YqiQ"
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' [[mmgA]]-[[mmgB]]-[[mmgC]]-[[mmgD]]-[[mmgE]]-[[yqiQ]] {{PubMed|8759838}} |
| − | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,8759838}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** expressed early during sporulation in the mother cell ([[SigE]]) {{PubMed|15699190,8759838}} | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|8759838}} | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | **[[CcpA]]: transcription repression {{PubMed|8759838}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>12706720,, </pubmed> | + | <pubmed>12706720,8759838 , 15699190</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:37, 20 November 2009
- Description: methylisocitrate lyase
| Gene name | yqiQ |
| Synonyms | prpB |
| Essential | no |
| Product | methylisocitrate lyase |
| Function | mother cell metabolism |
| Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A, Central C-metabolism | |
| MW, pI | 32 kDa, 5.279 |
| Gene length, protein length | 903 bp, 301 aa |
| Immediate neighbours | yqzF, mmgE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24120
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate (according to Swiss-Prot)
- Protein family: Methylisocitrate lyase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 1MUM (enzyme of E. coli)
- UniProt: P54528
- KEGG entry: [3]
- E.C. number: 4.1.3.30
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
