Difference between revisions of "AcpA"
| Line 74: | Line 74: | ||
* '''Interactions:''' [[AcpA]]-[[AcpS]], [[AcpA]]-[[BioI]] | * '''Interactions:''' [[AcpA]]-[[AcpS]], [[AcpA]]-[[BioI]] | ||
| − | * '''Localization:''' cytoplasm (according to Swiss-Prot) | + | * '''Localization:''' cytoplasm (according to Swiss-Prot), during sporulation in the mother cell {{PubMed|19850612}} |
=== Database entries === | === Database entries === | ||
| Line 91: | Line 91: | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[fapR]]-[[plsX]]-[[fabD]]-[[fabG]]-[[acpA]]'' {{PubMed|19850612}} | ||
| + | ** ''[[acpA]]'' {{PubMed|19850612}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[fapR]]'': [[SigA]] {{PubMed|16932747}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** ''[[fapR]]'': induced if the cells experience an accumulation of malonyl-CoA ([[FapR]]) {{PubMed|12737802}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[FapR]]: transcription repression {{PubMed|12737802}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 125: | ||
=References= | =References= | ||
| − | <pubmed>10997907,, </pubmed> | + | <pubmed>10997907,19850612, 12737802</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:52, 24 October 2009
- Description: acyl carrier protein
| Gene name | acpA |
| Synonyms | acpP |
| Essential | yes PubMed |
| Product | acyl carrier protein |
| Function | fatty acid biosynthesis |
| MW, pI | 8 kDa, 3.594 |
| Gene length, protein length | 231 bp, 77 aa |
| Immediate neighbours | fabG, rnc |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU15920
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot), during sporulation in the mother cell PubMed
Database entries
- UniProt: P80643
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mariano A Martinez, Diego de Mendoza, Gustavo E Schujman
Transcriptional and functional characterization of the gene encoding acyl carrier protein in Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 2);484-495
[PubMed:19850612]
[WorldCat.org]
[DOI]
(I p)
Gustavo E Schujman, Luciana Paoletti, Alan D Grossman, Diego de Mendoza
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Dev Cell: 2003, 4(5);663-72
[PubMed:12737802]
[WorldCat.org]
[DOI]
(P p)
K D Parris, L Lin, A Tam, R Mathew, J Hixon, M Stahl, C C Fritz, J Seehra, W S Somers
Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites.
Structure: 2000, 8(8);883-95
[PubMed:10997907]
[WorldCat.org]
[DOI]
(P p)
