Difference between revisions of "ThyB"
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* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| − | * '''Regulation:''' | + | * '''Regulation:''' weak induction in the presence of glucose ([[CcpN]]) {{PubMed|19732150}} |
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' [[CcpN]]: weak transcription activation {{PubMed|19732150}} |
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 19732150 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:20, 8 September 2009
- Description: thymidylate synthase B
| Gene name | thyB |
| Synonyms | |
| Essential | no |
| Product | thymidylate synthase B |
| Function | biosynthesis of thymidine nucleotides |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation) | |
| MW, pI | 30 kDa, 6.272 |
| Gene length, protein length | 792 bp, 264 aa |
| Immediate neighbours | dfrA, ypjQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU21820
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P11044
- KEGG entry: [2]
- E.C. number: 2.1.1.45
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
