Difference between revisions of "MalA"
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[malA]]-[[glvR]]-[[malP]]'' | + | * '''Operon:''' ''[[malA]]-[[glvR]]-[[malP]]'' {{PubMed|11489864}} |
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|11489864}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** induction by maltose ([[GlvR]]) {{PubMed|11489864}} | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|11489864}} | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[GlvR]]: transcription activation {{PubMed|11489864}} | ||
| + | ** [[CcpA]]: transcription repression {{PubMed|11489864}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 20:05, 31 August 2009
- Description: 6-phospho-alpha-glucosidase
| Gene name | malA |
| Synonyms | glvG, glvA |
| Essential | no |
| Product | 6-phospho-alpha-glucosidase |
| Function | maltose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 50 kDa, 4.74 |
| Gene length, protein length | 1347 bp, 449 aa |
| Immediate neighbours | yfjA, glvR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU08180
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Maltose 6'-phosphate + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 4 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: membrane associated PubMed
Database entries
- Structure: 1U8X
- UniProt: P54716
- KEGG entry: [3]
- E.C. number: 3.2.1.122
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
