Difference between revisions of "PhoB"
| Line 92: | Line 92: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[phoB]]-[[ydhF]]'' | + | * '''Operon:''' ''[[phoB]]-[[ydhF]]'' {{PubMed|10913081}} |
| − | * '''[[Sigma factor]]:''' [[SigA]], [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigA]], [[SigE]] {{PubMed|15699190,16030210}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed under conditions of phosphate limitation ([[PhoP]]) | + | ** expressed under conditions of phosphate limitation ([[PhoP]]) {{PubMed|9335276,10913081,16030210}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[PhoP]]: transcription activation | + | ** [[PhoP]]: transcription activation {{PubMed|9335276,10913081,16030210}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 119: | Line 119: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| − | |||
=Your additional remarks= | =Your additional remarks= | ||
Revision as of 18:42, 23 August 2009
- Description: alkaline phosphatase A
| Gene name | phoB |
| Synonyms | phoAIII |
| Essential | no |
| Product | alkaline phosphatase A |
| Function | aquisition of phosphate upon phosphoate starvation |
| Metabolic function and regulation of this protein in SubtiPathways: Folate | |
| MW, pI | 50 kDa, 5.895 |
| Gene length, protein length | 1386 bp, 462 aa |
| Immediate neighbours | ydhF, ydhG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU05740
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A phosphate monoester + H2O = an alcohol + phosphate (according to Swiss-Prot)
- Protein family: alkaline phosphatase family (according to Swiss-Prot)
- Paralogous protein(s): PhoA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on ser/ thr/ tyr PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: extracellular (signal peptide) PubMed
Database entries
- Structure:
- UniProt: P19405
- KEGG entry: [3]
- E.C. number: 3.1.3.1
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
