sufC
168

ABC transporter (ATP-binding protein), synthesis of Fe-S clusters

Locus

BSU_32710

Molecular weight

28.88 kDa

Isoelectric point

4.62

Protein length

261 aaSequenceBlast

Gene length

786 bpSequenceBlast

Function

synthesis of Fe-S clusters

Product

ABC transporter (ATP-binding protein)

Essential

yes

Synonyms

sufC, yurY

Outlinks

BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Hide small RNAsZoom:

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0396 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene

Coordinates

3,359,995 3,360,780

Phenotypes of a mutant

essential PubMed

the mutant is viable and Fe-S clusters are dispensable if IspG and IspH from the MEP pathway for isoprenoid biosynthesis are bypassed by a heterologous mevalonate pathway which allows B. subtilis to synthesize isopentenyl diphosphate and diphosphomevalonate PubMed

The protein

Catalyzed reaction/ biological activity

synthesis of Fe-S-clusters (the SufB-SufC-SufD complex) PubMed

Protein family

ABC transporter superfamily (according to UniProt)

Domains

ABC transporter domain (aa 6-248) (according to UniProt)

Structure

5AWF (PDB) (from E. coli, the SufB-SufC-SufD complex, 51% identity) PubMed

P80866 (AlphaFold)

Modification

phosphorylated on ser/ thr/ tyr PubMed