kre

kre
168

ComK repressor, stimulates degradation of the comK mRNA

Locus
BSU_14020
Molecular weight
17.75 kDa
Isoelectric point
10.17
Protein length
154 aaSequenceBlast
Gene length
465 bpSequenceBlast
Function
control of ComK accumulation and of bistable competence gene expression
Product
ComK repressor
Essential
no
Synonyms
kre, ykyB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,474,560  1,475,024
The protein
Catalyzed reaction/ biological activity
stimulates ComK mRNA degradation PubMed
controls stability of several mRNAs (see Kre regulon) PubMed
Structure
P42430 (AlphaFold)
Localization
cytoplasm PubMed
Expression and Regulation
Operons
Genes
kre
Description
PubMed
Regulation
repressed in competent cells (ComK) PubMed
Regulatory mechanism
ComK: repression, PubMed, in comK regulon
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kre

2025-03-21 22:04:50

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1C0577476FBB6BCEC41381B6F6677BD2DA922722

Biological materials
Mutant
MGNA-A764 (ykyB::erm), available at the NBRP B. subtilis, Japan
PG479 (ykyB::erm), available in Leendert Hamoen's and Jörg Stülke's labs PubMed
GP2533 (kre::erm), available in Jörg Stülke's lab
BKE14020 (kre::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATTTCTCTCCTTTGCT,  downstream forward: _UP4_TAAAATAAAAACAGCCGTGC
BKK14020 (kre::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATTTCTCTCCTTTGCT,  downstream forward: _UP4_TAAAATAAAAACAGCCGTGC
References
Reviews
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Original Publications
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Page visits: 3812

Time of last update: 2025-04-02 17:47:51

Author of last update: Jstuelk