prpE

prpE
168

protein tyrosine phosphatase

Locus
BSU_11630
Molecular weight
27.31 kDa
Isoelectric point
6.75
Protein length
244 aaSequenceBlast
Gene length
735 bpSequenceBlast
Function
unknown
Product
protein tyrosine phosphatase
Essential
no
E.C.
3.6.1.17
Synonyms
prpE, yjbP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
1,239,387 → 1,240,121
Phenotypes of a mutant
increased amounts of small aci-soluble spore proteins (SASPs) PubMed
The protein
Catalyzed reaction/ biological activity
H2O + P1,P4-bis(5'-adenosyl) tetraphosphate --> AMP + ATP + 2 H+PubMed
H2O + P1,P4-bis(5'-guanosyl) tetraphosphate --> GMP + GTP + 2 H+ (according to UniProt)
Protein family
prpE family (single member, according to UniProt)
Structure
4J6O (PDB) (PnkP from Thermocellum sp., 48% identity) PubMed
O31614 (AlphaFold)
Localization
forespore (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
prpE
Description
PubMed
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prpE

2025-03-15 16:24:42

ghost

65

2c0251eedea6376dfbcbb4b8da1317879bdc5b54

6C72C0328AC0656B139DE6D18E9E08ECB4A65C3E

Biological materials
Mutant
MGNA-B162 (yjbP::erm), available at the NBRP B. subtilis, Japan
BKE11630 (ΔprpE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGCGGTCTCCTCCTTACC,  downstream forward: _UP4_CGCCCCATATAAAAAAGGAG
BKK11630 (ΔprpE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGCGGTCTCCTCCTTACC,  downstream forward: _UP4_CGCCCCATATAAAAAAGGAG
References
Reviews
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Original Publications
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D1661093571DA4DEC5FBD8EDD3910879DAFDEE23

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Time of last update: 2025-04-03 22:04:39

Author of last update: Jstuelk