niaP

niaP
168

nicotinate transporter

Locus
BSU_02950
Molecular weight
43.55 kDa
Isoelectric point
9.5
Protein length
400 aaSequenceBlast
Gene length
1203 bpSequenceBlast
Function
uptake of niacin
Product
nicotinate transporter
Essential
no
Synonyms
niaP, yceI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
317,725  318,927
Phenotypes of a mutant
more sensitive to nisin PubMed
The protein
Protein family
major facilitator superfamily PubMed
Sugar transporter (TC 2.A.1.1) family (according to UniProt)
Domains
10 membrane-spanning domains PubMed
Structure
4J05 (PDB) (from P. indica, 24% identity) PubMed
O34691 (AlphaFold)
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
niaP
Description
PubMed
Regulation
repressed in the presence of nicotinic acid (NadR) PubMed
Regulatory mechanism
NadR: repression, PubMed, in nadR regulon
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niaP

2025-03-16 15:00:28

ghost

75

4f27939fcd082b95e84d1991ecac7d0c419db59a

2C36D9AAFCE9C373703AA3E1623020F68768C140

Biological materials
Mutant
MGNA-C047 (yceI::erm), available at the NBRP B. subtilis, Japan
BKE02950 (niaP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCCAACACCTCTGATA,  downstream forward: _UP4_TAGGAAAAGCACCTCTTAAA
BKK02950 (niaP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGCCAACACCTCTGATA,  downstream forward: _UP4_TAGGAAAAGCACCTCTTAAA
References
Reviews
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Original Publications
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0037A6808E75C2A2E207A7005EFDA71FCE90BAD8

Page visits: 2837

Time of last update: 2025-04-08 07:35:58

Author of last update: Melvin.boenninger