znuB

znuB
168

high-affinity ABC transporter for zinc (permease)

Locus
BSU_02870
Molecular weight
30.28 kDa
Isoelectric point
10.38
Protein length
280 aaSequenceBlast
Gene length
843 bpSequenceBlast
Function
zinc uptake
Product
ABC transporter for zinc (permease)
Essential
no
Synonyms
znuB, yceA, adcB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG1108 (Galperin et al., 2021)

This gene is a member of the following regulons

SigA regulon, Zur regulon

Gene
Coordinates
310,000 → 310,842
Phenotypes of a mutant
reduced genetic competence, can be rescued by the addition of excess zinc PubMed
reduced expression of the ''comFA-comFB-comFC-yvyF-flgM-flgN-flgK-flgL'' operon  PubMed
The protein
Protein family
ABC-3 integral membrane protein family (with MntC and MntD, according to UniProt)
Structure
O34610 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
znuA-znuC-znuB
Description
PubMed
Regulation
induced by zinc starvation (Zur) PubMed
Regulatory mechanism
Zur: repression, in the presence of zinc PubMed, in zur regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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znuA→znuB

2025-04-03 08:52:25

ghost

123

d84622c86cda894bc37d4650ce0ef2c146681ec6

DA65C8A158A0243655AECDC10E982F7866F2A4D9

Biological materials
Mutant
MGNA-B982 (yceA::erm), available at the NBRP B. subtilis, Japan
BKE02870 (ΔznuB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGACGGCGATCATGCCGC,  downstream forward: _UP4_TAACATGAAAAGCAGTTTTC
BKK02870 (ΔznuB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGACGGCGATCATGCCGC,  downstream forward: _UP4_TAACATGAAAAGCAGTTTTC
References
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EE212953BC83BD6D69BF769D6E917F4F954BE1E2

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Time of last update: 2025-04-05 13:04:06

Author of last update: Jstuelk