galK

galK
168

galactokinase

Locus
BSU_38200
Molecular weight
43.36 kDa
Isoelectric point
5.15
Protein length
390 aaSequenceBlast
Gene length
1173 bpSequenceBlast
Function
galactose utilization
Product
galactokinase
Essential
no
E.C.
2.7.1.6
Synonyms
galK, ipa-35d
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0153 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,920,638  3,921,810
The protein
Catalyzed reaction/ biological activity
α-D-galactose + ATP --> ADP + α-D-galactose 1-phosphate + H+ (according to UniProt)
Protein family
GHMP kinase family (together with IspE and ThrB) (according to UniProt)
Structure
1PIE (PDB) (from Lactococcus lactis, 43% identity, 60% similarity)\tPubMed
P39574 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
galK-galT
Description
PubMed
Regulation
repressed by glucose (CcpA) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Open in new tab

galK→galT

2025-02-27 00:23:22

ghost

70

603ab561182787ccf42180f9123596253729b2eb

7EAB5E2D27A9196B25E69B42DEED4992D71587AA

Genes
ywcC-gtcA-galK-galT
Description
PubMed
Regulation
repressed by glucose (CcpA) PubMed
Open in new tab

ywcC→galT

2025-04-08 03:17:06

ghost

132

2c55134f930fd735713cc2b5bc79db8a76ccbb71

EAEF4B4702CF0981CF8DC10BB149EDF4E1FB63DF

Biological materials
Mutant
BKE38200 (galK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGCAATCACCTTTCTG,  downstream forward: _UP4_AGAGAACTAAAGGGGGAGTG
BKK38200 (galK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGCAATCACCTTTCTG,  downstream forward: _UP4_AGAGAACTAAAGGGGGAGTG
References
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36930CC6FDFCA23D43E264FEA375B78A1434E1BD

Page visits: 6261

Time of last update: 2025-04-09 01:32:50

Author of last update: Melvin.boenninger