appB

appB
168

oligopeptide ABC transporter (permease)

Locus
BSU_11390
Molecular weight
35.25 kDa
Isoelectric point
9.77
Protein length
317 aaSequenceBlast
Gene length
951 bpSequenceBlast
Function
uptake of oligopeptides
Product
oligopeptide ABC transporter (permease)
Essential
no
Synonyms
appB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG0601 (Galperin et al., 2021)

This gene is a member of the following regulons

CodY regulon, ScoC regulon, TnrA regulon

Gene
Coordinates
1,215,243 → 1,216,193
The protein
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
OppBC subfamily (according to UniProt)
Domains
ABC transmembrane type-1 domain (aa 96-303) (according to UniProt)
Structure
P42062 (AlphaFold)
Paralogous protein(s)
DppB, OppB
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
appD-appF-appA/1-appA/2-appB-appC
Description
PubMed
Regulation
repressed by CodY PubMed
Regulatory mechanism
TnrA: activation, PubMed, in tnrA regulon
CodY: repression, PubMed PubMed, in codY regulon
ScoC: repression, PubMed, in scoC regulon
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appD→appC

2025-03-26 06:06:54

Jstuelk

128

b46f08a2cd8f8540d1ae7be3ab793fb86c3b4d9c

D515582AF1C173F5A0D9E2C830FC884903502563

Biological materials
Mutant
GP2100 (D(''appD-appF-appA/2-appB-appC)::spc''), available in Jörg Stülke's lab
BKE11390 (ΔappB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATACTTGTCCCCCTTTA,  downstream forward: _UP4_GAATATTAAAAGGAGGGAAA
BKK11390 (ΔappB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATACTTGTCCCCCTTTA,  downstream forward: _UP4_GAATATTAAAAGGAGGGAAA
References
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Page visits: 5783

Time of last update: 2025-04-04 17:35:23

Author of last update: Jstuelk