kipR

kipR
168

transcriptional repressor of the kip operon

Locus
BSU_04100
Molecular weight
27.16 kDa
Isoelectric point
5.43
Protein length
250 aaSequenceBlast
Gene length
753 bpSequenceBlast
Function
regulation of sporulation initiation
Product
transcriptional regulator
Essential
no
Synonyms
kipR, ycsO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1414 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
461,615  462,367
The protein
Domains
HTH iclR-type domain (aa 5-65) (according to UniProt)
IclR-ED (aa 80-249) (according to UniProt)
Structure
1MKM (PDB) (from Thermotoga maritima, 33% identity) PubMed
P42968 (AlphaFold)
Expression and Regulation
Operons
Genes
pxpA-ycsG-ycsI-pxpB-pxpC-kipR-lipC
Description
PubMed
Regulation
induced in the presence of 5-oxoproline PubMed
Regulatory mechanism
KipR: repression, PubMed, in kipR regulon
TnrA: activation, PubMed, in tnrA regulon
Open in new tab

pxpA→lipC

2025-04-03 06:02:48

Jstuelk

102

2e345e8dee0849e85fe094a123ef62dc61c60b82

B227AB4ADF5839F5D85D0A01462013A7CDA6A81D

Biological materials
Mutant
BKE04100 (kipR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCTGCATCATTCATCCCC,  downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
BKK04100 (kipR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCTGCATCATTCATCCCC,  downstream forward: _UP4_TAAGTAGCCAATCTTTTCTC
References
Loading

7DA9A79876C546B78B716A64706A3A3716018C2E

Page visits: 3634

Time of last update: 2025-04-03 20:50:31

Author of last update: Melvin.boenninger