YngG

• Description: 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
  
  

Gene name	yngG
Synonyms
Essential	no
Product	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
Function	biosynthesis of ketone bodies
MW, pI	32 kDa, 5.753
Gene length, protein length	897 bp, 299 aa
Immediate neighbours	yngF, yngH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate (according to Swiss-Prot)

• Protein family: HMG-CoA lyase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1YDO

• Swiss prot entry: O34873

• KEGG entry: BSU18230

• E.C. number: 4.1.3.4

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed