PurN

• Description: phosphoribosylglycinamide formyltransferase, irreversible
  
  

Gene name	purN
Synonyms
Essential	no
Product	phosphoribosylglycinamide formyltransferase
Function	purine biosynthesis
MW, pI	21 kDa, 6.182
Gene length, protein length	585 bp, 195 aa
Immediate neighbours	purM, purH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide (according to Swiss-Prot)

• Protein family: GART family (according to Swiss-Prot)

• Paralogous protein(s): YkkE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P12040

• KEGG entry: BSU06510

• E.C. number: 2.1.2.2

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed