AcoA

• Description: acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)
  
  

Gene name	acoA
Synonyms	yfjK
Essential	no
Product	acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)
Function	acetoin utilization
MW, pI	35 kDa, 4.912
Gene length, protein length	999 bp, 333 aa
Immediate neighbours	yfjL, acoB
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: acoA-acoB-acoC-acoL PubMed

• Sigma factor: SigL PubMed

• Regulation: induced by acetoin (AcoR) PubMed

• Regulatory mechanism: AcoR: transcription activation (interaction with SigL-containing RNA polymerase) PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Michel Debarbouille, Pasteur Institute, Paris, France Homepage

References

1. Ali, N. O., Bignon, J., Rapoport, G., and Débarbouillé, M. (2001) Regulation of the acetoin catabolic pathway is controlled by sigma L in Bacillus subtilis. J. Bacteriol. 183, 2497-2504. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed