Stusti 2018
Contents
- 1 Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
- 1.1 What makes RNA such a special molecule – specific chemical and structural features of RNA
- 1.2 RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
- 1.3 Ribozymes (catalytically active RNAs) (Intro)
- 1.4 The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
- 1.5 The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
- 1.6 Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
- 1.7 RNA-based second messengers
- 1.8 Riboregulation and virulence, targeting by antibiotics
- 1.9 Riboswitches
- 1.10 Protein- or tRNA-controlled RNA switches
- 1.11 RNA thermometers
- 1.12 The RNA world and evolution
- 1.13 RNA modification
- 1.14 RNA degradation/processing
- 1.15 Regulation by non-coding RNA
- 1.16 RNA dependent DNA Polymerases - from telomerase to retroviruses
- 1.17 RNA dependent RNA Polymerases – the RNA replicase
- 1.18 CRISPR/Cas: Science – the bacterial “immune” system
- 1.19 CRISPR/Cas: Application and groundbreaking perspectives
- 1.20 The mysterious function and role of 6S-RNA and pRNA in bacteria
- 1.21 Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
- 1.22 Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
- 1.23 Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
What makes RNA such a special molecule – specific chemical and structural features of RNA
David A Hiller, Scott A Strobel
The chemical versatility of RNA.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2929-35
[PubMed:21930584]
[WorldCat.org]
[DOI]
(I p)
RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
Ribozymes (catalytically active RNAs) (Intro)
David M J Lilley
Mechanisms of RNA catalysis.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2910-7
[PubMed:21930582]
[WorldCat.org]
[DOI]
(I p)
The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
RNA-based second messengers
Riboregulation and virulence, targeting by antibiotics
Riboswitches
Protein- or tRNA-controlled RNA switches
RNA thermometers
The RNA world and evolution
RNA modification
RNA degradation/processing
John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538]
[WorldCat.org]
[DOI]
(I p)
Soraya Aït-Bara, Agamemnon J Carpousis
RNA degradosomes in bacteria and chloroplasts: classification, distribution and evolution of RNase E homologs.
Mol Microbiol: 2015, 97(6);1021-135
[PubMed:26096689]
[WorldCat.org]
[DOI]
(I p)
Jonathan Houseley, David Tollervey
The many pathways of RNA degradation.
Cell: 2009, 136(4);763-76
[PubMed:19239894]
[WorldCat.org]
[DOI]
(I p)
Regulation by non-coding RNA
RNA dependent DNA Polymerases - from telomerase to retroviruses
RNA dependent RNA Polymerases – the RNA replicase
CRISPR/Cas: Science – the bacterial “immune” system
CRISPR/Cas: Application and groundbreaking perspectives
The mysterious function and role of 6S-RNA and pRNA in bacteria
Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
