Stusti 2018
Contents
- 1 Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
- 1.1 What makes RNA such a special molecule – specific chemical and structural features of RNA
- 1.2 RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
- 1.3 Ribozymes (catalytically active RNAs) (Intro)
- 1.4 The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
- 1.5 The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
- 1.6 Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
- 1.7 RNA-based second messengers
- 1.8 Riboregulation and virulence, targeting by antibiotics
- 1.9 Riboswitches
- 1.10 Protein- or tRNA-controlled RNA switches
- 1.11 RNA thermometers
- 1.12 The RNA world and evolution
- 1.13 RNA modification
- 1.14 RNA degradation/processing
- 1.15 Regulation by non-coding RNA
- 1.16 RNA dependent DNA Polymerases - from telomerase to retroviruses
- 1.17 RNA dependent RNA Polymerases – the RNA replicase
- 1.18 CRISPR/Cas: Science – the bacterial “immune” system
- 1.19 CRISPR/Cas: Application and groundbreaking perspectives
- 1.20 The mysterious function and role of 6S-RNA and pRNA in bacteria
- 1.21 Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
- 1.22 Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
- 1.23 Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
What makes RNA such a special molecule – specific chemical and structural features of RNA
RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
Ribozymes (catalytically active RNAs) (Intro)
The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
Panagiotis Papasaikas, Juan Valcárcel
The Spliceosome: The Ultimate RNA Chaperone and Sculptor.
Trends Biochem Sci: 2016, 41(1);33-45
[PubMed:26682498]
[WorldCat.org]
[DOI]
(I p)
Yan Wang, Jing Liu, B O Huang, Yan-Mei Xu, Jing Li, Lin-Feng Huang, Jin Lin, Jing Zhang, Qing-Hua Min, Wei-Ming Yang, Xiao-Zhong Wang
Mechanism of alternative splicing and its regulation.
Biomed Rep: 2015, 3(2);152-158
[PubMed:25798239]
[WorldCat.org]
[DOI]
(P p)
A Gregory Matera, Zefeng Wang
A day in the life of the spliceosome.
Nat Rev Mol Cell Biol: 2014, 15(2);108-21
[PubMed:24452469]
[WorldCat.org]
[DOI]
(I p)
Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
RNA-based second messengers
Riboregulation and virulence, targeting by antibiotics
Riboswitches
Protein- or tRNA-controlled RNA switches
RNA thermometers
The RNA world and evolution
RNA modification
RNA degradation/processing
Regulation by non-coding RNA
RNA dependent DNA Polymerases - from telomerase to retroviruses
RNA dependent RNA Polymerases – the RNA replicase
CRISPR/Cas: Science – the bacterial “immune” system
CRISPR/Cas: Application and groundbreaking perspectives
The mysterious function and role of 6S-RNA and pRNA in bacteria
Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
Sujin Jeong, Seung Ryul Han, Young Ju Lee, Seong-Wook Lee
Selection of RNA aptamers specific to active prostate-specific antigen.
Biotechnol Lett: 2010, 32(3);379-85
[PubMed:19943183]
[WorldCat.org]
[DOI]
(I p)
Regina Stoltenburg, Christine Reinemann, Beate Strehlitz
SELEX--a (r)evolutionary method to generate high-affinity nucleic acid ligands.
Biomol Eng: 2007, 24(4);381-403
[PubMed:17627883]
[WorldCat.org]
[DOI]
(P p)
