Stusti 2018

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

• Riboswitches

• Riboregulation and virulence, targeting by antibiotics

• RNA-based second messengers

• Ribozymes

Yigong Shi
Mechanistic insights into precursor messenger RNA splicing by the spliceosome.
Nat Rev Mol Cell Biol: 2017, 18(11);655-670
[PubMed:28951565] [WorldCat.org] [DOI] (I p)

Olga Novikova, Marlene Belfort
Mobile Group II Introns as Ancestral Eukaryotic Elements.
Trends Genet: 2017, 33(11);773-783
[PubMed:28818345] [WorldCat.org] [DOI] (I p)

Yigong Shi
The Spliceosome: A Protein-Directed Metalloribozyme.
J Mol Biol: 2017, 429(17);2640-2653
[PubMed:28733144] [WorldCat.org] [DOI] (I p)

Nayef Jarrous
Roles of RNase P and Its Subunits.
Trends Genet: 2017, 33(9);594-603
[PubMed:28697848] [WorldCat.org] [DOI] (I p)

David M J Lilley
How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes.
Biochem Soc Trans: 2017, 45(3);683-691
[PubMed:28620029] [WorldCat.org] [DOI] (I p)

Marcos de la Peña, Inmaculada García-Robles, Amelia Cervera
The Hammerhead Ribozyme: A Long History for a Short RNA.
Molecules: 2017, 22(1);
[PubMed:28054987] [WorldCat.org] [DOI] (I e)

Jennifer Gebetsberger, Ronald Micura
Unwinding the twister ribozyme: from structure to mechanism.
Wiley Interdiscip Rev RNA: 2017, 8(3);
[PubMed:27863022] [WorldCat.org] [DOI] (I p)

Michele Felletti, Jörg S Hartig
Ligand-dependent ribozymes.
Wiley Interdiscip Rev RNA: 2017, 8(2);
[PubMed:27687155] [WorldCat.org] [DOI] (I p)

Sabine Müller, Bettina Appel, Darko Balke, Robert Hieronymus, Claudia Nübel
Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?
F1000Res: 2016, 5;
[PubMed:27408700] [WorldCat.org] [DOI] (P e)

Bradley P Klemm, Nancy Wu, Yu Chen, Xin Liu, Kipchumba J Kaitany, Michael J Howard, Carol A Fierke
The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions.
Biomolecules: 2016, 6(2);
[PubMed:27187488] [WorldCat.org] [DOI] (I e)

Matthew W L Lau, Adrian R Ferré-D'Amaré
In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffold.
Methods: 2016, 106;76-81
[PubMed:27130889] [WorldCat.org] [DOI] (I p)

Randi M Jimenez, Julio A Polanco, Andrej Lupták
Chemistry and Biology of Self-Cleaving Ribozymes.
Trends Biochem Sci: 2015, 40(11);648-661
[PubMed:26481500] [WorldCat.org] [DOI] (I p)

• Protein- or tRNA-controlled RNA switches

Jinwei Zhang, Adrian R Ferré-D'Amaré
Structure and mechanism of the T-box riboswitches.
Wiley Interdiscip Rev RNA: 2015, 6(4);419-33
[PubMed:25959893] [WorldCat.org] [DOI] (I p)

Anna V Sherwood, Frank J Grundy, Tina M Henkin
T box riboswitches in Actinobacteria: translational regulation via novel tRNA interactions.
Proc Natl Acad Sci U S A: 2015, 112(4);1113-8
[PubMed:25583497] [WorldCat.org] [DOI] (I p)

Tina M Henkin
The T box riboswitch: A novel regulatory RNA that utilizes tRNA as its ligand.
Biochim Biophys Acta: 2014, 1839(10);959-963
[PubMed:24816551] [WorldCat.org] [DOI] (P p)

• RNA thermometers

• The RNA world and evolution

Ádám Kun, Ádám Radványi
The evolution of the genetic code: Impasses and challenges.
Biosystems: 2018, 164;217-225
[PubMed:29031737] [WorldCat.org] [DOI] (I p)

Thomas Fouqueau, Fabian Blombach, Finn Werner
Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation.
Annu Rev Microbiol: 2017, 71;331-348
[PubMed:28657884] [WorldCat.org] [DOI] (I p)

Eugene V Koonin, Artem S Novozhilov
Origin and evolution of the genetic code: the universal enigma.
IUBMB Life: 2009, 61(2);99-111
[PubMed:19117371] [WorldCat.org] [DOI] (I p)

Yuri I Wolf, Eugene V Koonin
On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization.
Biol Direct: 2007, 2;14
[PubMed:17540026] [WorldCat.org] [DOI] (I e)

• RNA modification

Baixing Wu, Li Li, Ying Huang, Jinbiao Ma, Jinrong Min
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Curr Opin Struct Biol: 2017, 47;67-76
[PubMed:28624569] [WorldCat.org] [DOI] (I p)

Hiroyuki Hori
Transfer RNA methyltransferases with a SpoU-TrmD  (SPOUT) fold and their modified nucleosides in  tRNA.
Biomolecules: 2017, 7(1);
[PubMed:28264529] [WorldCat.org] [DOI] (I e)

Ajay K Rana, Serge Ankri
Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases.
Front Genet: 2016, 7;99
[PubMed:27375676] [WorldCat.org] [DOI] (P e)

Marcus Fislage, Lina Wauters, Wim Versées
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers: 2016, 105(8);568-79
[PubMed:26832457] [WorldCat.org] [DOI] (I p)

• RNA degradation/ processing

John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538] [WorldCat.org] [DOI] (I p)

• CRISPR/Cas: Science

• CRISPR/Cas: Application