Stusti 2018

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Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

  • Riboswitches


  • Riboregulation and virulence, targeting by antibiotics


  • RNA-based second messengers


  • Ribozymes


  • Protein- or tRNA-controlled RNA switches

Jinwei Zhang, Adrian R Ferré-D'Amaré
Structure and mechanism of the T-box riboswitches.
Wiley Interdiscip Rev RNA: 2015, 6(4);419-33
[PubMed:25959893] [WorldCat.org] [DOI] (I p)

Anna V Sherwood, Frank J Grundy, Tina M Henkin
T box riboswitches in Actinobacteria: translational regulation via novel tRNA interactions.
Proc Natl Acad Sci U S A: 2015, 112(4);1113-8
[PubMed:25583497] [WorldCat.org] [DOI] (I p)

Tina M Henkin
The T box riboswitch: A novel regulatory RNA that utilizes tRNA as its ligand.
Biochim Biophys Acta: 2014, 1839(10);959-963
[PubMed:24816551] [WorldCat.org] [DOI] (P p)


  • RNA thermometers

Satya Narayan, Mamta H Kombrabail, Sudipta Das, Himanshu Singh, Kandala V R Chary, Basuthkar J Rao, Guruswamy Krishnamoorthy
Site-specific fluorescence dynamics in an RNA 'thermometer' reveals the role of ribosome binding in its temperature-sensitive switch function.
Nucleic Acids Res: 2015, 43(1);493-503
[PubMed:25477380] [WorldCat.org] [DOI] (I p)


  • The RNA world and evolution


  • RNA modification

Baixing Wu, Li Li, Ying Huang, Jinbiao Ma, Jinrong Min
##Title##
Curr Opin Struct Biol: 2017, 47;67-76
[PubMed:28624569] [WorldCat.org] [DOI] (I p)

Hiroyuki Hori
Transfer RNA methyltransferases with a SpoU-TrmD  (SPOUT) fold and their modified nucleosides in  tRNA.
Biomolecules: 2017, 7(1);
[PubMed:28264529] [WorldCat.org] [DOI] (I e)

Ajay K Rana, Serge Ankri
Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases.
Front Genet: 2016, 7;99
[PubMed:27375676] [WorldCat.org] [DOI] (P e)

Marcus Fislage, Lina Wauters, Wim Versées
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers: 2016, 105(8);568-79
[PubMed:26832457] [WorldCat.org] [DOI] (I p)


  • RNA degradation/ processing


  • CRISPR/Cas: Science



  • CRISPR/Cas: Application