Transcription factors of the GntR family

A large family of transcription factors. DNA-binding occurs via a winged helix-turn-helix motif and is mostly controlled by low molecular weight effectors. The family has four subfamilies, that differ in their effector-binding domains.

Members of the HutC subfamily in B. subtilis

• FrlR
• GamR
• GmuR
• NagR
• TreR
• YmfC
• YydK

Members of the YtrA subfamily in B. subtilis

• YhcF
• YtrA

Members of the FadR subfamily in B. subtilis

• GntR
• YcbG

Additional GntR family regulator

• LutR
• YdhC

Transcription factors with a DNA-binding domain of the GntR family, but different effector-binding domain

• AraR