GltT

• Description: major high-affinity Na+-coupled glutamate/ aspartate symport protein
  
  

Gene name	gltT
Synonyms	yhfG
Essential	no
Product	major Na+-coupled glutamate/ aspartate symport protein
Function	glutamate and aspartate uptake
Gene expression levels in SubtiExpress: gltT
Metabolic function and regulation of this protein in SubtiPathways: gltT
MW, pI	45 kDa, 9.029
Gene length, protein length	1287 bp, 429 aa
Immediate neighbours	yhfF, yhfH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins

The gene

Basic information

• Locus tag: BSU10220

Phenotypes of a mutant

• impaired uptake of glutamate and aspartate PubMed

Database entries

• BsubCyc: BSU10220

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s): GltP, DctP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane PubMed

Database entries

• BsubCyc: BSU10220

• Structure:
  • 4IZM (the protein from Pyrococcus horikoshii, 35% identity, 73% similarity) PubMed
  • 4KY0 (the glutamate transporter of Thermococcus kodakarensis, 35% identity, 72% similarity) PubMed

• UniProt: O07605

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: gltT PubMed

• Expression browser: gltT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 254 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 2407 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: