YumC

• Description: ferredoxin/flavodoxin-NAD(P)+ oxidoreductase
  
  

Gene name	yumC
Synonyms
Essential	yes PubMed
Product	ferredoxin/flavodoxin reductase
Function	redox reactions that involve ferredoxin and flavodoxin
Gene expression levels in SubtiExpress: yumC
Interactions involving this protein in SubtInteract: YumC
MW, pI	36 kDa, 5.573
Gene length, protein length	996 bp, 332 aa
Immediate neighbours	yumB, yuzG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

electron transport/ other, essential genes

The gene

Basic information

• Locus tag: BSU32110

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU32110

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 2 reduced ferredoxin or flavodoxin + NADP⁺ + H⁺ = 2 oxidized ferredoxin or flavodoxin + NADPH (according to Swiss-Prot)

• Protein family: ferredoxin-NADP reductase type 2 family (according to Swiss-Prot)

• Paralogous protein(s): YcgT

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: active site Cys85 is S-bacillithiolated by NaOCl stress in B. subtilis and other Bacillus species PubMed

• Cofactors: FAD PubMed

• Effectors of protein activity:

• Interactions:
  • dimeric protein PubMed
  • YumC-YkuN (electron transfer from NADPH via YumC to YkuN) PubMed

• Localization:

Database entries

• BsubCyc: BSU32110

• Structure: 3LZW PubMed

• UniProt: O05268

• KEGG entry: [2]

• E.C. number: 1.18.1.2

Expression and regulation

• Operon:

• Expression browser: yumC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 5753 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 9972 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 5216 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 2849 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 3293 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: