divIB

divIB
168

cell-division initiation protein (septum formation)

Locus
BSU_15240
Molecular weight
30.02 kDa
Isoelectric point
9.24
Protein length
Gene length
Function
septum formation
Product
cell-division protein, member of the divisome
Essential
yes
Synonyms
divIB, dds, tms-12

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1589 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,593,704 → 1,594,495
Phenotypes of a mutant
essential PubMed
The protein
Protein family
FtsQ/DivIB family (single member, according to UniProt)
POTRA domain (aa 54-123) (according to UniProt)
Structure
2ALJ (PDB) (major extracytoplasmic domain, Geobacillus stearothermophilus)
cell membrane PubMed
Expression and Regulation
Operons
Description
Regulation
expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
Regulatory mechanism
SpoIIID: repression, PubMed, in spoIIID regulon
Sigma factors
SigM: sigma factor, (promoter within MurG) PubMed, in sigM regulon
SigA: sigma factor, PubMed, in sigA regulon
SigE: sigma factor, PubMed, in sigE regulon
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murGsbp

2025-04-07 16:32:38

Jstuelk

116

5a24cdfec598f0a2424898f47e06e5544408d3d6

1A7F525A9A274FAF9AE05A426F5AE7383E95D9E3

Description
Regulation
expressed during vegatative growth PubMed
Regulatory mechanism
stringent response: negative regulation, in stringent response
SpoIIID: repression, PubMed, in spoIIID regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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murEsbp

2025-04-07 16:30:23

Jstuelk

118

68c6899b3f1263bd636c35a4ea9512c00078a714

2F040145AC628A38E3D11955965F4DA256DE6790

Description
Regulation
expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
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spoVEsbp

2025-04-07 21:54:08

Jstuelk

134

6fa043950e40c3a1d4f91339581472acb9db18da

C066C3357FB70D8EEB595C678C068B56731F8F59

Description
Open in new tab

divIBsbp

2025-04-07 21:34:04

Jstuelk

107

f37d9a564efeec39a2ef7291ea255a7cf0bf6960

DC16386FDAC4B973DDD9A4C0BCD3FF866F63C22D

Description
Regulation
expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
Open in new tab

murBsbp

2025-04-07 21:19:10

Jstuelk

156

3d08ab9489a62734a3c1b81d0d7a7e15bf37e1dc

F5945D130AA23B8820F36AD12C2F42D0A674910E

Biological materials
FLAG-tag construct
GP2005 divIB-3xFLAG ermC (based on pGP1087), available in Jörg Stülke's lab
References
Reviews
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Original Publications
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B66FC02948DABBCE64DE2629D6E33E05647B4EEF

Page visits: 6389

Time of last update: 2025-04-09 06:44:08

Author of last update: Jstuelk