Rtp

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  • Description: replication terminator protein

Gene name rtp
Synonyms
Essential no
Product replication terminator protein
Function replication termination
Gene expression levels in SubtiExpress: rtp
MW, pI 14 kDa, 9.778
Gene length, protein length 366 bp, 122 aa
Immediate neighbours proH, yoxD
Sequences Protein DNA DNA_with_flanks
Genetic context
Rtp context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Rtp expression.png















Categories containing this gene/protein

DNA replication

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU18490

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds to nine termination sites spanning ∼430 kb of the replication terminus region PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1F4K (complex with DNA), 1BM9
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 50 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Daniel L Kaplan, Deepak Bastia
Mechanisms of polar arrest of a replication fork.
Mol Microbiol: 2009, 72(2);279-85
[PubMed:19298368] [WorldCat.org] [DOI] (I p)

Original publications