sdpR

sdpR
168

transcriptional repressor (ArsR family) of the sdpR-sdpI operon

Locus
BSU_33790
Molecular weight
10.10 kDa
Isoelectric point
7.33
Protein length
90 aaSequenceBlast
Gene length
273 bpSequenceBlast
Function
regulation of protection against SdpC
Product
transcriptional regulator (ArsR family)
Essential
no
Synonyms
sdpR, yvbA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0640 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,467,054  3,467,326
The protein
Protein family
ArsR family
Domains
HTH arsR-type domain (aa 1-87) (according to UniProt)
Structure
2CWE (PDB) (from Pyrococcus horikoshii, 34% identity)
O32242 (AlphaFold)
Effectors of protein activity
SdpI binds and sequesters SdpR if extracellular SdpC is present, this results in induction of the ''sdpR-sdpI'' operon PubMed
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
sdpR-sdpI
Description
PubMed
Regulation
induced by extracellular SdpC (SdpR) PubMed
Regulatory mechanism
AbrB: repression, PubMed, in abrB regulon
SdpR: repression, PubMed, in sdpR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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sdpR→sdpI

2025-04-06 15:34:00

ghost

102

5d445ea25a72afe4e546a9c2c315acdd558698ea

9D4EA374978198F0CA6504590736099562B4ED12

Biological materials
Mutant
BKE33790 (sdpR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC,  downstream forward: _UP4_TTATGAAGAAAAATATAATT
BKK33790 (sdpR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCGTTTTCTCCTTTAC,  downstream forward: _UP4_TTATGAAGAAAAATATAATT
References
Reviews
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Original Publications
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29A3EC8FB0C763A973273AA14EAEB904847C3002

Page visits: 3578

Time of last update: 2025-04-09 00:44:34

Author of last update: Melvin.boenninger