Condensin
Contents
- 1 Condensin is a conserved protein complex that binds the origin region of the DNA. It is required for segregation of the origin regions after DNA replication.
- 2 Mutants lacking condensin components are viable as long as they grow slowly (i.e. on minimal medium), but the components are essential for rapid growth (on LB).
- 3 Localization of the condensin complex depends on Spo0J.
- 4 The condensin complex: Smc2-ScpA-ScpB
- 5 Important publications
Condensin is a conserved protein complex that binds the origin region of the DNA. It is required for segregation of the origin regions after DNA replication.
Mutants lacking condensin components are viable as long as they grow slowly (i.e. on minimal medium), but the components are essential for rapid growth (on LB).
Localization of the condensin complex depends on Spo0J.
The condensin complex: Smc2-ScpA-ScpB
Important publications
Thomas G W Graham, Xindan Wang, Dan Song, Candice M Etson, Antoine M van Oijen, David Z Rudner, Joseph J Loparo
ParB spreading requires DNA bridging.
Genes Dev: 2014, 28(11);1228-38
[PubMed:24829297]
[WorldCat.org]
[DOI]
(I p)
Stephan Gruber, Jan-Willem Veening, Juri Bach, Martin Blettinger, Marc Bramkamp, Jeff Errington
Interlinked sister chromosomes arise in the absence of condensin during fast replication in B. subtilis.
Curr Biol: 2014, 24(3);293-8
[PubMed:24440399]
[WorldCat.org]
[DOI]
(I p)
Xindan Wang, Olive W Tang, Eammon P Riley, David Z Rudner
The SMC condensin complex is required for origin segregation in Bacillus subtilis.
Curr Biol: 2014, 24(3);287-92
[PubMed:24440393]
[WorldCat.org]
[DOI]
(I p)
Sophie Nolivos, David Sherratt
The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes.
FEMS Microbiol Rev: 2014, 38(3);380-92
[PubMed:24118085]
[WorldCat.org]
[DOI]
(I p)
