YtpB

• Description: tetraprenyl-beta-curcumene synthase, salt stress protein
  
  

Gene name	ytpB
Synonyms
Essential	no
Product	tetraprenyl-beta-curcumene synthase
Function	C35 terpenoid biosynthesis
Gene expression levels in SubtiExpress: ytpB
MW, pI	42 kDa, 5.755
Gene length, protein length	1101 bp, 367 aa
Immediate neighbours	ytqB, ytpA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

• Locus tag: BSU30500

Database entries

• BsubCyc: BSU30500

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU30500

• Structure:

• UniProt: O34707

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ytpA-ytpB PubMed
  • ytpB PubMed

• Expression browser: ytpB PubMed

• Sigma factor:
  • ytpA: SigM Pubmed

• Regulation:
  • expressed under conditions of salt stress (SigM) Pubmed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tsutomu Sato
Unique biosynthesis of sesquarterpenes (C35 terpenes).
Biosci Biotechnol Biochem: 2013, 77(6);1155-9
[PubMed:23748782] [WorldCat.org] [DOI] (I p)

Tsutomu Sato, Satoru Yoshida, Hiroko Hoshino, Mizuki Tanno, Mami Nakajima, Tsutomu Hoshino
Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase.
J Am Chem Soc: 2011, 133(25);9734-7
[PubMed:21627333] [WorldCat.org] [DOI] (I p)

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)