ggt

ggt
168

gamma-glutamyltransferase

Locus
BSU_18410
Molecular weight
64.01 kDa
Isoelectric point
5.45
Protein length
Gene length
Function
degradation of poly-glutamate capsules
Product
gamma-glutamyltransferase
Essential
no
E.C.
2.3.2.2
Synonyms
ggt, pac

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0405 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,004,677  2,006,440
The protein
Catalyzed reaction/ biological activity
α-amino acid + N-terminal (5-L-glutamyl)-[peptide] --> 5-L-glutamyl amino acid + N-terminal L-α-aminoacyl-[peptide] (according to UniProt)
glutathione + H2O --> L-cysteinylglycine + L-glutamate (according to UniProt)
S-substituted glutathione + H2O --> S-substitued L-cysteinylglycine + L-glutamate (according to UniProt)
Protein family
gamma-glutamyltransferase family (with YwrD, according to UniProt)
Structure
extracellular (signal peptide) PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
strongly induced in response to glucose starvation in M9 medium PubMed
Additional information
translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
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ggt

2025-03-27 23:59:04

ghost

77

a43d94dd582f261584f02a2bbe87ef072613582c

6AD798C23482E70A48481DFCEFE25962BB8DA435

Biological materials
Mutant
BKE18410 (ggt::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCTCCCTCCTATATG,  downstream forward: _UP4_TAAATAAAAAACTGTACTCG
BKK18410 (ggt::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTTCTCCCTCCTATATG,  downstream forward: _UP4_TAAATAAAAAACTGTACTCG
References
Reviews
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Original Publications
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5C31D968E3786858B025CE02CFAC48F61700031F

Page visits: 5186

Time of last update: 2025-04-08 19:53:03

Author of last update: Jstuelk