gntK

gntK
168

gluconokinase

Locus
BSU_40060
Molecular weight
57.00 kDa
Isoelectric point
5.52
Protein length
513 aaSequenceBlast
Gene length
1542 bpSequenceBlast
Function
gluconate utilization
Product
gluconokinase
Essential
no
E.C.
2.7.1.12
Synonyms
gntK
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1070 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,114,141  4,115,682
The protein
Catalyzed reaction/ biological activity
ATP + D-gluconate --> 6-phospho-D-gluconate + ADP + H+ (according to UniProt)
Protein family
FGGY kinase family (according to UniProt)
Structure
3GBT (PDB) (from Lactobacillus acidophilus, 39% identity)
P12011 (AlphaFold)
Expression and Regulation
Operons
Genes
gntR-gntK-gntP-gntZ
Description
PubMed
Regulation
induced by gluconate (GntR) PubMed
Regulatory mechanism
GntR: repression, PubMed, in gntR regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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gntR→gntZ

2025-04-08 12:06:59

ghost

86

a4a9f34acee86d883fafe2368089737d1c13df10

02F8B40AEEBB8D4A2614150F30482A3F72134EF4

Biological materials
Mutant
BKE40060 (gntK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
BKK40060 (gntK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
References
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72404FA6ECD62AEA3EFDB934DFB8DA581875605C

Page visits: 3349

Time of last update: 2025-04-12 15:04:38

Author of last update: Melvin.boenninger