YetL

• Description: transcriptional repressor of yetM and yetL, induction in response to flavonoids
  
  

Gene name	yetL
Synonyms
Essential	no
Product	transcription repressor (MarR family)
Function	regulation of yetM expression
Gene expression levels in SubtiExpress: yetL
MW, pI	19 kDa, 7.518
Gene length, protein length	501 bp, 167 aa
Immediate neighbours	yetK, yetM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

The YetL regulon:

• yetM

The gene

Basic information

• Locus tag: BSU07220

Database entries

• BsubCyc: BSU07220

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: inducers: flavonoids of kaempferol, apigenin, and luteolin PubMed

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU07220

• Structure:

• UniProt: O31541

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yetL PubMed

• Expression browser: yetL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 92 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Kazutake Hirooka, Yusuke Danjo, Yuki Hanano, Satoshi Kunikane, Hiroshi Matsuoka, Shigeo Tojo, Yasutaro Fujita
Regulation of the Bacillus subtilis divergent yetL and yetM genes by a transcriptional repressor, YetL, in response to flavonoids.
J Bacteriol: 2009, 191(11);3685-97
[PubMed:19329649] [WorldCat.org] [DOI] (I p)