NhaC

• Description: Na+/H+ antiporter
  
  

Gene name	nhaC
Synonyms	yheL
Essential	no
Product	Na+/H+ antiporter
Function	pH homeostasis
Gene expression levels in SubtiExpress: nhaC
Metabolic function and regulation of this protein in SubtiPathways: NhaC
MW, pI	47 kDa, 7.874
Gene length, protein length	1359 bp, 453 aa
Immediate neighbours	dat, nhaX
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), pH homeostasis, membrane proteins

The gene

Basic information

• Locus tag: BSU09680

Database entries

• BsubCyc: BSU09680

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)

• Paralogous protein(s): MleN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU09680

• Structure:

• UniProt: O07553

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: nhaC PubMed

• Expression browser: nhaC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • NhaX: transcription activation (probably) PubMed

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: