YhfQ

• Description: iron/ citrate ABC transporter (solute-binding protein)
  
  

Gene name	yhfQ
Synonyms
Essential	no
Product	iron/ citrate ABC transporter (solute-binding protein)
Function	iron uptake
Gene expression levels in SubtiExpress: yhfQ
Interactions involving this protein in SubtInteract: YhfQ
Metabolic function and regulation of this protein in SubtiPathways: yhfQ
MW, pI	38 kDa, 9.303
Gene length, protein length	1044 bp, 348 aa
Immediate neighbours	yhfP, yhfR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU10330

Database entries

• BsubCyc: BSU10330

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YfmF-(YfmD-YfmE)-(YfmC-YhfQ) PubMed

• Localization:
  • associated to the membrane (via YfmD-YfmE) PubMed

Database entries

• BsubCyc: BSU10330

• Structure:

• UniProt: C0SP94

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhfQ PubMed

• Sigma factor:

• Regulation:
  • repressed unless the cells enter an iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)