GlxB

• Description: glyoxalase II
  
  

Gene name	glxB
Synonyms	yurT
Essential	no
Product	glyoxalase II
Function	detoxification of methylglyoxal
Gene expression levels in SubtiExpress: glxB
Metabolic function and regulation of this protein in SubtiPathways: GlxB
MW, pI	14 kDa, 4.609
Gene length, protein length	381 bp, 127 aa
Immediate neighbours	yurS, yuzN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress

The gene

Basic information

• Locus tag: BSU32660

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • S-lactoyl-bacillithiol (BSH) --> D-lactate + BSH PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O32161

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: glxB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Pete Chandrangsu, Renata Dusi, Chris J Hamilton, John D Helmann
Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol-dependent and independent pathways.
Mol Microbiol: 2014, 91(4);706-15
[PubMed:24330391] [WorldCat.org] [DOI] (I p)