YqeI

From SubtiWiki
Revision as of 14:16, 2 April 2014 by 134.76.38.147 (talk)
Jump to: navigation, search
  • Description: similar to predicted RNA-binding protein, may be involved in ribosome assembly

Gene name yqeI
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yqeI
MW, pI 10 kDa, 9.476
Gene length, protein length 288 bp, 96 aa
Immediate neighbours nadD, aroD
Sequences Protein DNA DNA_with_flanks
Genetic context
YqeI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqeI expression.png















Categories containing this gene/protein

translation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25650

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • the protein is enriched in 45S assembly intermediates that accumulate upon depletion of RbgA PubMed
  • The E. coli homolog: yhbY
  • The homolog from E. coli associates to the 50S subunit of the ribosome and is involved in ribosome assembly Ecocyc

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1LN4 (the YhbY protein of E. coli, 41% identity, 62% similarity) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • YqeI might be a RNA-binding protein PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ningning Li, Yuling Chen, Qiang Guo, Yixiao Zhang, Yi Yuan, Chengying Ma, Haiteng Deng, Jianlin Lei, Ning Gao
Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit.
Nucleic Acids Res: 2013, 41(14);7073-83
[PubMed:23700310] [WorldCat.org] [DOI] (I p)

Alison Hunt, Joy P Rawlins, Helena B Thomaides, Jeff Errington
Functional analysis of 11 putative essential genes in Bacillus subtilis.
Microbiology (Reading): 2006, 152(Pt 10);2895-2907
[PubMed:17005971] [WorldCat.org] [DOI] (P p)

Gerard J Ostheimer, Alice Barkan, Brian W Matthews
Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins.
Structure: 2002, 10(11);1593-601
[PubMed:12429100] [WorldCat.org] [DOI] (P p)