Ggt

• Description: gamma-glutamyltransferase
  
  

Gene name	ggt
Synonyms	pac
Essential	no
Product	gamma-glutamyltransferase
Function	degradation of poly-glutamate capsules
Gene expression levels in SubtiExpress: ggt
MW, pI	64 kDa, 5.453
Gene length, protein length	1761 bp, 587 aa
Immediate neighbours	yoeD, yofA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU18410

Database entries

• BsubCyc: BSU18410

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • extracellular (signal peptide) PubMed

Database entries

• BsubCyc: BSU18410

• Structure: 2V36

• UniProt: P54422

• KEGG entry: [2]

• E.C. number: 2.3.2.2

Expression and regulation

• Operon: ggt PubMed

• Expression browser: ggt PubMed

• Sigma factor:

• Regulation:
  • strongly induced in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: