RpsO

• Description: ribosomal protein
  
  

Gene name	rpsO
Synonyms
Essential	yes PubMed
Product	ribosomal protein S15 (BS18)
Function	translation
Gene expression levels in SubtiExpress: rpsO
Interactions involving this protein in SubtInteract: RpsO
MW, pI	10 kDa, 10.975
Gene length, protein length	267 bp, 89 aa
Immediate neighbours	ribC, pnpA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU16680

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU16680

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ribosomal protein S15P family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • 23S rRNA-S15 PubMed
  • 16S rRNA-S15 PubMed

• Localization:

Database entries

• BsubCyc: BSU16680

• Structure: 1A32 (Geobacillus stearothermophilus)

• UniProt: P21473

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: rpsO PubMed

• Expression browser: rpsO PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed
  • translational repression of rpsO expression upon binding of excess RpsO to a RNA switch in the untranslated region of the rpsO mRNA PubMed

• Regulatory mechanism:

• Additional information:
  • the mRNA is processed, this is initiated by RNase Y and cleavage products are subsequently subject to exonucleolytic degradation by RNases J1 and J2 and by PNPase PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: