CypC

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  • Description: long chain-fatty acid beta-hydroxylating cytochrome P450, H(2)O(2)-dependent, hydroxylates myristic acid to beta-hydroxymyristic acid, required for protection against paraquat stress

Gene name cypC
Synonyms ybdT
Essential no
Product fatty acid beta-hydroxylating cytochrome P450, protection against paraquat stress
Function biosynthesis of beta-hydroxy fatty acid for lipopeptides
Gene expression levels in SubtiExpress: cypC
MW, pI 47 kDa, 6.468
Gene length, protein length 1251 bp, 417 aa
Immediate neighbours ybxI, ybyB
Sequences Protein DNA DNA_with_flanks
Genetic context
CypC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CypC expression.png















Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, electron transport/ other, lipid metabolism/ other

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU02100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hydroxylation of a long-chain fatty acid (e.g. myristic acid) at the alpha- and beta-positions using hydrogen peroxide as an oxidant PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: cypC (according to DBTBS)
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References