Condensin

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== Condensin is a conserved protein complex that binds the origin region of the DNA. It is required for segregation of the origin regions after DNA replication.

Mutants lacking condensin components are viable as long as they grow slowly (i.e. on minimal medium), but the components are essential for rapid growth (on LB).

Loclization of the condensin complex depends on Spo0J.==

The condensin complex: Smc2-ScpA-ScpB

Important publications

Stephan Gruber, Jan-Willem Veening, Juri Bach, Martin Blettinger, Marc Bramkamp, Jeff Errington
Interlinked sister chromosomes arise in the absence of condensin during fast replication in B. subtilis.
Curr Biol: 2014, 24(3);293-8
[PubMed:24440399] [WorldCat.org] [DOI] (I p)

Xindan Wang, Olive W Tang, Eammon P Riley, David Z Rudner
The SMC condensin complex is required for origin segregation in Bacillus subtilis.
Curr Biol: 2014, 24(3);287-92
[PubMed:24440393] [WorldCat.org] [DOI] (I p)